While B12 is naturally present in animal-based foods such as meat, fish, and dairy, many people struggle to get adequate amounts due to dietary restrictions, absorption issues, or certain medical conditions
Here SAM acts as a methyl donor which is actually formed with the help of vitamin B12
[95] Intramuscular or intravenous injection [edit] Injection of hydroxycobalamin is often used if digestive absorption is impaired, [2] but this course of action may not be necessary with high-dose oral supplements (such as 0.51.0 mg or more), [97] [98] because with large quantities of the vitamin taken orally, even the 1% to 5% of free crystalline B 12 that is absorbed along the entire intestine by passive diffusion may be sufficient to provide a necessary amount
Intrinsic factor is produced by the cells that line your stomach, and is one of the main components that drives your B12 intake capacity
There are some nerves running through the shoulder and there is always a slight chance a needle may hit a nerve if the injection location is incorrect
REF-0232 (v7.0) 1/2021