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Measurement of the levels of intracellular GSH and the relative expression of NRF2, GPX4 and SOD1 in tissue samples following neoadjuvant chemotherapy To further verify the role of GSH metabolism in chemotherapy resistance, we analyzed breast cancer data from the Gene Expression Omnibus (GEO) dataset (GEO: GSE140494)
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In vitro challenge with Mycobacterium avium demonstrated enhanced immune clearance post-treatment, suggesting that glutathione primes immune defense mechanisms relevant to neuroinflammatory conditions
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