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Numerous other nutritional factors such as selenium, thiamine, riboflavin, as well as pyridoxine, cobalamin, folate, and minerals such as magnesium and zinc, aid in the methylation process, also contribute to the synthesis of glutathione

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Primary enzymes, including superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx), play a crucial role in neutralizing free radicals

Dixon et al., 2011)

Acknowledgements We thank all the members of the Mostoslavsky laboratory for critical discussions throughout the years and editing of the manuscript, especially T