Muscle Aches and Lactic Acid Buildup: Improved mitochondrial function means the body relies less on inefficient anaerobic energy production during minor exertion, which may reduce the painful buildup of lactic acid in the muscles
Cell 154 , 10851099 (2013)
Supporting liver detox and cellular health
De Luca, A., Hartinger, C
PHGDH inhibition not only results in reduced TAM infiltration and a restrained immunosuppressive phenotype but also leads to the inhibition of tumor growth and partial restoration of anti-tumor immunity [199]
Therefore, maintaining a balance between ROS production and scavenging is essential for preserving engineered stem cell function and ensuring overall organismal health, underscoring their importance in regenerative medicine, disease modeling, and drug screening