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During treatment, blood tests and neurological examinations must be performed

Providers should regularly assess body composition using DEXA or InBody scans to ensure lean mass preservation

Adding a second compound while still experiencing significant adverse effects from the first makes it impossible to isolate which agent is responsible for new or worsening symptoms

While safety monitoring was comprehensive, the trials were not specifically designed to detect rare adverse effects that might occur at rates lower than 1-2%, which would require much larger participant numbers

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