Low levels have been associated with irritability, low energy, and mood fluctuations
Product Attributes CAS # : 1034043-18-3 Molecular Formula : C10H11N2+ (free base), C10H11IN2 (iodide salt), C10H11ClN2 (chloride salt) Sequence (AA) : N/A (small molecule) Molecular Weight : 215.26 g/mol PubChem CID : 950107 (free base), 66522933 (iodide salt) Half-Life : 3.8-6.9 hours Synonyms : 5-Amino-1-methylquinolinium-1-ium, NNMT Inhibitor 5A1MQ, NNMTi, Amino-1MQ, 1-MQ, Type : Synthetic small molecule analog Research Focus : Weight Loss, Mitochondrial Function, Longevity, Metabolic Health Scientific References Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice Animal Roles of nicotinamide N-methyltransferase in obesity and type 2 diabetes mellitus Review What is 5-Amino-1MQ
Individuals at risk of vitamin B12 deficiency include vegetarians and vegans, older adults, individuals with gastrointestinal disorders, and those who have undergone certain medical procedures such as bariatric surgery
A 42-year-old woman developed an immediate reaction to intramuscular cyanocobalamin B12, despite positive intradermal testing
Experimental findings also suggest that NNMT inhibition may enhance stem cell activity and support regenerative responses in skeletal muscle tissue, making it a compound of interest in ongoing biochemical and metabolic research
Anti-Inflammatory Effects & Mucosal Protection Chronic inflammation underlies many GI conditions, from Crohns disease to IBS
