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Reduction of Abdominal and Visceral Fat : Animal and early human models have demonstrated a preferential reduction of abdominal fat following subcutaneous administration of AOD-9604

This shapes the entire dosing approach: you want enough to maximize receptor engagement, not more

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As we age, it is often more difficult to absorb B12 from our food

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Pharmacokinetic profiles for the compound place its plasma half-life in the neighborhood of 45 minutes after parenteral administration in animal models, which informs typical dosing intervals in published experiments