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Here, we discuss key findings pertinent to our current discussion, that is direct neurotransmitter effects on adult NSCs and pharmacological studies that have attempted to augment adult neurogenesis in vitro and in vivo

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Clinical Insight Social isolation is a potent, biologically mediated driver of negative affect and aggressionpartly via tachykinin 2 signalingwith preclinical evidence that NK3 receptor antagonism can normalize isolation-induced aggression, fear, and anxiety without sedation

Concentrations of GSH and GSSG were calculated from the IS calibration by interpolating the constructed linear-regression curves, with the analyte to IS peak ratios measured from sample solutions

References (1) Flanagan JL, et al

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