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The number of nucleoli and the expression of nucleolar proteins increased when Rpl15 was overexpressed, and abnormal increases in nucleolar size and number caused by dysregulation of ribosome biogenesis have emerged as hallmarks of the majority of spontaneous cancers 42

Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or References Roofthooft DW, Simons SH, Anand KJ et al , Eight years later are we still hurting newborn infants

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