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Single-oocyte transcriptome analysis reveals aging-associated effects influenced by life stage and calorie restriction

174 Mei et al found that estrogen could inhibit autophagy in endometrial stromal cells (ESCs) by up-regulating the expression of chemokine CXCL12 and CXCR4 (the receptor of CXCL12)

Rebyota (fecal microbiota suspension) launched in US 2023 first approved FMT product

20,21 Although postnatal NAC supplementation in preterm infants failed to confer any significant benefit on mortality and morbidity, 22 several studies suggest NAC administration per partum to pregnant women with chorioamnionitis cases improved neonatal outcomes, as attested by a reduction in the need for intensive resuscitation, and in the risk of intraventricular hemorrhage (IVH) and BPD, compared to placebo

Approximately 95% of the oxygen consumed is reduced to water during aerobic metabolism, but the remaining fraction may be converted to reactive oxygen species and other free radicals, inducing oxidative stress

This protects fragile peptide chains from shear