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Klotho Peptides# Evidence Level: Primate data | FDA Status: Not approved Klotho peptides are derived from alpha-klotho, a transmembrane protein whose loss causes accelerated aging and whose overexpression extends lifespan in mice

2.1 Renal Impairment Study 2.1.1 Study Population Male and female participants of non-childbearing potential were eligible for inclusion in the renal impairment study if they were aged between 18 and 80 years with a body mass index (BMI) between 20 and 39.9 kg/m 2 and a body weight 60 kg at screening

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The potential of fatty acids and their derivatives as antifungal agents: a review

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L-Carnitine also plays a role in maintaining membrane integrity by regulating the acetyl-CoA/CoA ratio within mitochondria [57]