doi: 10.1097/01.md.0000172299.72364.95
The leading search terms were: oxidative stress, reactive oxygen species, thyroid disease, nutritional antioxidants, thyroid-gut axis, gut microbiome, and antioxidant probiotics
While numerous pathogenic mechanisms and potential targets have been identified, most mechanistic evidence (approximately 90%) relies on rodent models (e.g., mice, rats), representing a critical limitation
So far we lack a comprehensive mechanistic picture of the dynamics of the glutathione pool in the IMS, including its crosstalk with neighbouring compartments and redox pathways
K.Mohi-Ud-DinM.et al
doi: 10.1038/s44324-024-00007-4 183 XingEBilliACGudjonssonJE