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Drug Metab Pharmacokinet 30, 231239

An additional consideration is that the IGF-3/IGF-1 ratio may be an important factor determining the level of GH stimulation [3]

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2 Micale et al 2021 Around 10% of those with generalised joint hypermobility have accompanying physical and/or psychological symptoms , 3 and are therefore eligible for assessment for a diagnosis of a Heritable Connective Tissue Disorder like hypermobile EDS (hEDS), or a Hypermobility Spectrum Disorder

Increased Water Retention This is a classic sign of elevated growth hormone levels