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discovered that lactate from melanoma stimulates sterol regulatory element-binding protein 2 (SREBP2) in tumor DCs, leading to the transformation of conventional DCs into cluster of differentiation 63 (CD63)+ mature regulatory DCs (mregDCs) through homeostatic or tolerogenic maturation

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10.1101/cshperspect.a041193 Cold Spring Harb

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Researchers have also observed that Thymosin Beta-4 is associated with metalloproteinase regulation and anti-inflammatory signaling through NF-B pathway modulation

doi: 10.5501/wjv.v10.i5.229 2 BrobergEKHukkanenV