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[CrossRef] [PubMed] [Google Scholar] Clinical guidelines for the management of treatment-resistant depression: French recommendations from experts, the French Association for Biological Psychiatry and Neuropsychopharmacology and the fondation FondaMental

Toxicology and applied pharmacology 257 , 338348, doi: 10.1016/j.taap.2011.09.017 (2011)

2019;47 Suppl 2:38-44

Is 5-on/2-off better than dosing every day

Sleep is equally relevant: testosterone is primarily produced during sleep, and research has found that even one week of sleeping five hours per night reduces testosterone levels by approximately 10 to 15% in young men, a reduction equivalent to ageing ten to fifteen years