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Bignon J, Khoury F, Even P, Andre J, Brouet G: Morphometric study in chronic obstructive bronchopulmonary disease

Szatkowski J, Schwartz RA

Controlled human trials exist, but they're limited in size, focused mostly on topical cosmetic use, and usually last only a few weeks or months. That means a lot of the exciting claims, especially around gene expression, systemic repair, and anti-aging effects, haven't been confirmed in large-scale human studies

However, this doesnt mean it should be used without medical guidance

Studies have shown that Nrf2 activators, such as sulforaphane (SFN), can significantly reduce the generation of lipid peroxidation products by increasing GPX4 levels, thereby alleviating ferroptosis-induced damage to chondrocytes (Mahn and Castillo, 2021)

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