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We know cortisol is a direct neurotoxin

11.4 Personalized nutrition, nutrigenomics, and nutrigenetics Given the substantial inter-individual variability in gut microbiota composition, future nutritional strategies are expected to increasingly emphasize dietary personalization tailored to an individuals unique microbial profile

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Mechanisms include modulation of gonadotropin release, local growth factor activity, anti-inflammatory action, and stress-hormone reduction