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To evaluate the formation of mineralized precipitates and lipid vacuoles, after the differentiation period, alizarin red and adipo oil red staining were performed on undifferentiated and differentiated hGMSCs

Whereas the monomers and the protofilaments are harmless, the oligomers are cytotoxic and induce cell death in primary neuronal cells, fibroblasts, and neuroblastoma cells [69]

foaming and vigorous agitation are avoided during preparation

This structural change shifts fat cells toward a high-energy state that actively burns lipids via uncoupling protein 1 (UCP1) activation, providing deep insights into correcting metabolic dysfunction

and oxidation via the cytochrome, P450-dependent, mixed-function oxidase enzyme pathway to form a reactive intermediate metabolite, which conjugates with glutathione and is then further metabolized to form cysteine and mercapturic acid conjugates

doi: 10.1016/j.cca.2013.02.032