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Foundational Discovery Selective Senolytic Elimination in Aged Mice (Cell, 2017 Baar et al.) FOXO4-DRI Restores Fitness, Fur Density, Renal and Liver Function in Aged Mice The foundational study introducing FOXO4-DRI as a senolytic peptide was published in Cell by Baar and colleagues in 2017

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Chronic selenium supplementation risks toxicity, with case reports of selenosis highlighting the narrow therapeutic margin (287)

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Immunosuppressive Therapy In cases where antihistamines or other drugs are unable to remedy chronic urticaria, physicians can prescribe immunosuppressing medicines