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Bisulfite sequencing revealed that GEN induced methylation of a CpG island in the promoter region of Sfrp5, and this hypermethylated region overlapped with the H3Ac-depleted fragment, indicating cooperative gene repression through both DNA and histone modification ( To understand the mechanism of DKK1 upregulation, the researchers analyzed both DNA methylation and histone modification at the DKK1 promoter region
Figure 1C presents the growth curves of NOS3 cells exposed to various PTX concentrations
Opioid receptors, including the , , and subtypes, are members of the GPCR family
In contrast to initial reports placing GSH synthesis to both plastids and cytoplasm, the first enzyme of the pathway, -glutamylcysteine synthetase, is strictly localized in plastids, at least in Arabidopsis (Wachter et al., 2005)
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