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Description

Experiments have shown that female mice lacking Ambra-1 displayed autism-like behavior, supporting the findings of inhibited autophagy in ASD [286]

10.23785/TU.2024.05.006 39 EckenstalerR.BenndorfR

Administered at a dose of 1200 mg/kg, the treatment significantly downregulated NF-B levels, a key driver of neuroinflammation, showcasing strong anti-apoptotic and anti-inflammatory effects (Qi et al., 2019)