10.1162/089976602753712954 29 EngertF.BonhoefferT
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At the same time, lanosterol accumulation enhances membrane fluidity and increases ROS production, thereby boosting phagocytic activity, bacterial clearance, and survival in murine models of endotoxin shock [34]
Chan SH, Tai MH, Li CY, Chan JY: Reduction in molecular synthesis or enzyme activity of superoxide dismutases and catalase contributes to oxidative stress and neurogenic hypertension in spontaneously hypertensive rats
Boosted by the successes of FDA-approved Adcetris and Kadcyla , this drug class has been rapidly growing along with about 60 ADCs currently in clinical trials
