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Although Wilsons disease always begins with liver involvement, many patients may be asymptomatic and therefore go undiagnosed until they present at 2030 years of age with advanced hepatic or neurologic disease

Peptides, due to their complex amino acid sequences and inherently sensitive molecular architecture, are particularly vulnerable to environmental stressors

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The IL-22-responsive transcriptional module is significantly enriched in both mouse colitis models and human UC, with elevated levels of neutrophil-active chemokines such as Cxcl1 , Cxcl2 , Cxcl3 , and Cxcl5 [94]