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Compared to normal joints, the extracellular matrix of RAM of RA boasts a higher-content of a series of inflammatory factors, matrix metalloproteinases (MMP), many kinds of RONS, H + , while simultaneously exhibiting a lower concentration of oxygen [7]

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Our study provides the mechanistic basis for understanding roGFP2 redox sensing and challenges previous mechanisms for protein disulfide reduction

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482,483 Biomarkers play a crucial role in patient selection, biological effect detection, dose optimization, and monitoring response progress, with recent approvals of A monoclonal antibodies benefiting from new and accurate biomarkers

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