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[1] From this theory, we can propose that stimulating IGF-1 in skin tissue may be a potential effective treatment for regulating skin cell differentiation, improving insulin sensitivity in the skin, reducing keratinocyte proliferation, inhibiting inflammation via stimulation of IL-10 production and up-regulating sebocyte proliferation (via IGF-1 stimulation of 5-Reductase)
Centenarians maintain miRNA biogenesis pathway while it is impaired in octogenarians
impact of cholesterol, gender and age
Mechanism studies showed that DAF-16 and HSP-90 gene expression levels were up-regulated