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Currently, there are still relatively few research articles focusing on the palmitoylation modification of histones in tumor cells

For some, results appear gradually over the first week

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This dilemma underscores the importance of achieving redox balance rather than solely focusing on reducing oxidative markers [83]

Notably, regarding the specific types of PIPN-related ROS, H 2 O 2 has been confirmed to induce oxidative DNA damage in sensory neuronal cells and cause PIPN ( 2 (Sumkhemthong et al., 2021) might also play pivotal roles in the development of PIPN