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Hollow needles deliver serum during channel formation

Certain groupssuch as older adults, vegetarians, individuals with gastrointestinal disorders, and those taking specific medications (e.g., metformin or proton pump inhibitors)may develop a B12 deficiency

Only inject if there is no blood present

Rather than binding to a single receptor like most drugs, this peptide influences numerous biological pathways simultaneously

Special population studies, including evaluation in elderly patients, patients with significant comorbidities, and patients with organ dysfunction, would help establish safety profiles for diverse clinical populations

10.1021/jm300687e 45 Prez-SnchezH.den HaanH.Prez-GarridoA.Pea-GarcaJ.ChakrabortyS.Erdogan OrhanI.et al (2021)