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In addition, it has been described that oxidized cardiolipin modulates the biophysical properties of OMM to allow oligomerized Bax to insert and permeabilize the OMM ( GLUTATHIONE IMPORT TO MITOCHONDRIA As indicated above, despite the fact that the concentration of mGSH is high, GSH is not synthesized de novo in the mitochondrial matrix, as this organelle lacks the enzymes required for GSH synthesis
The study results revealed that the Imiquimod loaded polymeric nanoparticles showed greater efficacy against tumors followed by the marketed Imiquimod formulation and placebo showing the enhanced effectiveness of the Nano formulation approach over the conventional formulation of Imiquimod [249]
[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Schrag M, Mueller C, Oyoyo U, Smith MA, Kirsch WM
Effect of immobilized cell-binding peptides on chitosan membranes for osteoblastic differentiation of mesenchymal stem cells