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doi: 10.1111/mmi.12149 75 KwonHKKimGCKimYHwangWJashASahooAet al

19 Overexpression of NRF2 upregulates the expression of anti-apoptotic factors, downregulates pro-apoptotic proteins, and activates Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) and its downstream factors, such as ETS-Like Transcription Factor 1 (ELK1), Ribosomal Protein S6 Kinase, 70 kDa (P70S6K), and 90 kDa Ribosomal S6 Kinase (P90RSK)