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The underlying mechanisms of the protective effects of statins may involve inhibition of oncogene MYC, protein kinase B (AKT), and NF-B pathways by statins, leading to the enhanced cytokine production of interleukin-6 (IL-6), tumor necrosis factor- (TNF), and transforming growth factor-1(TGF-1) (Li et al., 2020a)

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