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Virus-like particles in vaccine development

Using the well-characterized 143B mitochondrial cybrid model 50 , we demonstrated that mtDNA mutant cells are more sensitive to 5FU treatment (Fig

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To confirm that haem-assisted dimerization of PGRMC1 occurs in solution, we analysed the structure of apo- and haem-bound PGMRC1 by two-dimensional nuclear magnetic resonance (NMR) using heteronuclear single-quantum coherence and transverse relaxation-optimized spectroscopy (Supplementary Figs 6b and 7)

However, this chemical process includes complex reaction processes and low yield, resulting in high cost and low purity of -EC, limiting the production of -EC for physical function investigations and medical/pharmaceutical applications