Stacked Protocol (AOD + MOTS-c) Dose: 0.5 mg AOD + 10 mg MOTS-c (= 20 clicks) Duration: 4 weeks Frequency: Daily Cycle Interval: Optional 2-week pause Goal / Description: 2 weeks off, then repeat or switch to MOTS-c only maintenance Possible Side Effects AOD-9604 is generally well-tolerated in research settings
The symptoms that matter most are the ones that suggest a more serious problem: severe abdominal pain, facial or throat swelling, blistering rash, major drops in urine output, or low blood sugar symptoms after a medication change
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Beveridge et al., 2014
Toll-like receptor misrecognition is considered to be an important step in alpha-synucleinopathy progression, and increased intestinal permeability, immune activation, and enteric neuroglial activation are keys in the pathophysiology of Parkinsons disease (158)
If youve shaken the vial vigorously, we would advise against using it in your research as its integrity may be compromised