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Interestingly, lycopene also reactivated GSTP1 gene expression through reduced promoter methylation in MDA-MB-468 breast cancer cells (King-Batoon et al., 2008)

*Correspondence: Xiaolong Jin, [email protected] ORCID: Xiaolong Jin, orcid.org/0009-0009-6522-6258 Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Traditional pain medications like NSAIDs, opioids, and corticosteroids can provide short-term relief but carry risks including side effects, dependency, and long-term health consequences