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For instance, EVs from cumulus cells carry miR-224, which targets Smad4 in oocytes to promote their maturation ( In the male reproductive system, EVs from Sertoli cells (Sertoli-EVs) provide vital support to developing germ cells in the seminiferous tubules, delivering nutrients, miRNAs, and proteins essential for spermatogenesis (James et al., 2020
& Sasaki, R
On the other hand, astrocyte depletion in the chronic phase of MS resulted in disease attenuation and reduced inflammatory infiltrate (107)
doi: 10.3389/fmed.2018.00028 12 Centers for Disease Control and Prevention (2024)
With respect to fatty acid metabolism, CYP2E1 catalyzes the microsomal (-1)- and (-2)-hydroxylation of saturated fatty acids and the epoxidation of unsaturated fatty acids
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