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Nevertheless, whether 15-LOX participates in the maintenance of skin homeostasis by triggering ferroptosis through lipid peroxidation remains to be further explored (Figure 2)

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#1: Pumpkin Seed Oil Antioxidants: decrease oxidation, decrease transforming growth factor beta Linoleic acid: decreases COX-2 enzyme #2: Rosemary Oil Polyphenols: decreases COX-2 enzyme Volatile oils: decreases COX-2 enzyme, interleukins, and tumor necrosis factor Recap: Direct Vs

Mild fluid retention or headaches may occur

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