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Only slight reversible creatinine decreases at very high doses (2 mg/kg) were noted

The sodium chloride content also helps to stabilize the pH level of the reconstituted solution

However, to maximize their shelf life and ensure consistent results, proper storage and reconstitution methods must be followed

Conservative dosing, interval monitoring, clear stopping criteria, and documentation rigorous enough that the data contributes to the evidence base rather than just adding another anecdote

Ebba Nex is an esteemed expert in the field of B12 with many publications in her name and is Professor emerita at Aarhus University Hospital, Department of Clinical Medicine where she is involved in research in various aspects of mainly biomarkers for B12 status

J Am Med Dir Assoc