Stability testing of active pharmaceutical ingredients and finished pharmaceutical products
Moreover, most studies have assessed individual metabolic parameters in isolation rather than the full MetS spectrum, further limiting causal interpretation of GFD-related metabolic changes
These microbial shifts trigger cascading gutbrain disruption by impairing neurotransmitter signaling, suppressing SCFA production, weakening epithelial barrier integrity, and activating neuroimmune pathways, ultimately resulting in anxiety- and depression-like behaviors in rodent models (Tejkalov et al., 2023
Pascoli, V., Cahill, E., Bellivier, F., Caboche, J
Gut microbiota changes were analyzed at phylum (Firmicutes, Bacteroidetes, Proteobacteria, Actinobacteria and Verrucomicrobia) and genus level ( Bifidobacterium, Lactobacillus, Clostridium, Ruminococcus, Akkermansia, Escherichia, Allobaculum, Blautia, Staphylococcus, Prevotella, Bacteroides, Turicibacter, Corynebacterium, Roseburia, Coprococcus )
PMCID: PMC10867874
