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2016) and testicular injury (Klinefelter et al

Additionally, its levels can decline with age

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Thus, future studies are needed to fully investigate the complex biological impact of NTAPP on the entire hair mini-organ

E3 ligases in metabolic diseases Insulin receptors and insulin receptor substrates (IRS-1 and IRS-2) are crucial for insulin signaling, and E3 ligases such as MG53, c-Cbl, and Nedd4 can directly degrade these substrates, disrupting signaling and promoting insulin resistance

Magnesium is a crucial intracellular cation cofactor for numerous enzymes involved in insulin metabolism [144]