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Increased permeability without severe mucosal damage is caused by tight junction protein abnormalities, whereas severe mucosal damage disrupts the barrier and causes uncontrolled leakage of the luminal contents

The abdomen is the most commonly used site and the easiest for self-administration

Any references to product characteristics, including but not limited to stability, preservation, or composition, are provided solely for general informational purposes within a research context and do not imply suitability for any other use

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The nominated uses included chronic insomnia, narcolepsy and opioid withdrawal, with a proposed subcutaneous formulation

Traumatic Brain Injury Support: There is ongoing research into whether Dihexa could aid in the recovery of cognitive function following injuries, though more rigorous human data is needed