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The pathophysiology of sarcopenia/atrophy is multifactorial and involves complex interactions between oxidative stress, chronic low-grade inflammation, hormonal alterations, and metabolic dysregulation

10.1073/pnas.1423088112 [DOI] [PMC free article] [PubMed] Kelly MP (2018) Cyclic nucleotide signaling changes associated with normal aging and age-related diseases of the brain

Swiercz R, Chiguru S, Tahmasbi A, Ramezani SM, Hao G, Challa DK, et al

Pathologically, SCI involves two phases: the primary injury, caused by direct mechanical trauma, and the secondary injury, driven by biochemical cascades including oxidative stress, inflammation, and regulated cell death (234, 235)

Novel genes associated with amyotrophic lateral sclerosis: Diagnostic and clinical implications

Janus membranes patch achieves high-quality tendon repair: inhibiting exogenous healing and promoting endogenous healing