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Malate plays an essential role in generating NADPH, which helps increase the NADPH/NADP + ratio and supports the cell's redox balance

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Some progress has been made in many aspects, from the cellular level to the molecular biological level, from experiment to clinic, catalpol shows considerable therapeutic promise, but its clinical application is limited by the intricate biochemical pathways it affects

Following absorption from the Gastrointestinal tract, paracetamol is metabolised predominantly in the liver where it is conjugated into inactive glucuronide and sulphate conjugates, which are excreted in urine, and toxic N-acetyl-p-benzoquinone imine (NAPQI), which is detoxified by glutathione

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Lai C-M, Xu J, Zhang B-C, He S-H, Shao J-W