Cellular senescence promotes adverse effects of chemotherapy and cancer relapse
LactMed notes that several studies on its effects on lactation are unable to offer valid conclusions because of their lack of blinding, randomization, and placebo control.48 However, there's at least one randomized control trial of particular relevance here because it used a combination of goat's rue and a silymarin phytosome
Approximately 0.3% (1:300) of patients of European or African ancestry have two loss-of-function alleles of the TPMT gene and have little or no TPMT activity (homozygous deficient or poor metabolizers), and approximately 10% of patients have one loss-of-function TPMT allele leading to intermediate TPMT activity (heterozygous deficient or intermediate metabolizers)
Rossotti FJC, Rossotti H (1965) Potentiometric titrations using Gran plots: a textbook omission
It's suggested that taking L-carnitine could be particularly beneficial for couples trying to conceive, with a recommended dosage of 1 to 3 grams per day for optimal effects 1 2
Oral arguments took place in December 2024, but the appellate court has yet to issue a decision