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Anyone diagnosed with pernicious anemiaan autoimmune condition preventing B12 absorptionrequires injections as oral supplements prove ineffective

Diabetes/metabolism Res Rev (2023) 39(2):e3596

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In drug-resistant breast cancer cells, GPER stabilizes the expression of hypoxia-inducible factor 1 alpha (HIF-1), regulating the glycolytic metabolism of tumor cells and promoting metabolic reprogramming [230]

Furthermore, derivatives of PA play a significant regulatory role in tumor resistance processes