Eur Rev Med Pharmacol Sci (2017) 21:89101
2018 Nov Ioannis Zalachoras, Fiona Hollis, Eva Ramos-Fernndez, Laura Trovo, Sarah Sonnay, Eveline Geiser, Nicolas Preitner, Pascal Steiner, Carmen Sandi, Laia Morat
First, using germ-free animals, directional microbiota transplantation, and gene editing techniques to clarify the causal mechanisms by which protective genera such as Bifidobacterium regulate the hepcidin-FPN1 axis and key molecules of chondrocyte ferroptosis (GPX4, SLC7A11), thereby consolidating the logical chain of microbiota-iron metabolism-cell death. Second, leveraging longitudinal cohorts and multi-omics technologies to reveal the time-dependent evolution of the gut dysbiosis-iron overload-ferroptosis-intestinal dysfunction cycle and identify key windows for early intervention
Blumberg Multivitamins That Are Actually Worth Taking by Charles Thorp, NASM Do Chlorophyll Supplements Work
When 15 lipoxygenase 1 (15LO1), a lipid-peroxidizing enzyme abundant in asthmatic human airway epithelial cells (HAECs), binds phosphatidylethanolamine-binding protein 1 (PEBP1), hydroperoxy-phospholipids, which drive ferroptotic cell death, are generated
[ Links ] 70
