There is also some evidence suggesting that high doses of B12 may lead to negative health outcomes in those with diabetes or kidney disease
Higher therapeutic doses range from 500-1000 mcg daily, with some protocols reaching 1500 mcg for specific conditions
Until recently, HSL was believed to be the primary enzyme responsible for virtually all TAG and DAG hydrolase activity in adipocytes, as well as neutral cholesteryl ester hydrolase (NCEH) activity
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