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The collagen work is solid, well-replicated across models

Androgens (including testosterone), estrogen and progesterone are the predominant gonadal sex hormones expressed by the testes or ovaries

Skin barrier repair Commercial epidermal tissues EpiSkin (L'Oral Research and Innovation Center, Shanghai, China) is an in vitro reconstructed human epidermis (RHE) from normal human keratinocytes and is similar to the in vivo human epidermis

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Ethics statement All aspects of the animal studies and all protocols met the accepted criteria for the care and experimental use of laboratory animals, and were approved by the Animal Research Committee of the 1st Faculty of Medicine, Charles University in Prague (under registration No