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Individuals with certain health conditions, such as Lebers disease (a hereditary eye disease), should avoid B12 injections, as they can exacerbate symptoms

This rapid clearance might suggest the need for larger doses, yet the peptide initiates cellular processes that continue long after the compound itself has been metabolized

Knezevic, M

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Cells 12 (1), 90

CT-996, Carmot Therapeutics) are in current clinical development for obesity