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Because B12 is water-soluble, the NIH Office of Dietary Supplements notes that no tolerable upper intake level has been established excess B12 is excreted by the body rather than accumulating to toxic levels

Results observed in one study or experimental model should not be expected in every research setting

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Adiponutrin Adiponutrin is a 45 kDa patatin domaincontaining protein that is highly expressed primarily in adipose tissue (9)

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Researchers have investigated its potential involvement in metabolic signaling, energy balance mechanisms, and biochemical regulation processes