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It's just that the body's response to it is not, it's too much too strong

An immediate and then sustained effect on pressure in lower esophageal sphincter, and a postponed effect on pyloric sphincter after either 0.5 mg/kg or 1.0 mg/kg intraperitoneal challenge (white bars), pyloric sphincter seems to be less affected

10.1186/1476-9255-9-16 32 Granados-CastroL

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This leads to improper metabolism and lack of energy

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