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In contrast, a GSSR intermediate was detected and its decreased steady-state concentration at higher glutaredoxin concentrations was suggested to support monothiol mechanism (i) 60

Reactive oxygen species (ROS) production is increased via COVID-19-induced mitochondrial damage and activation of NADPH oxidase ( SARS-CoV-2 can cause the immune system to strongly release various cytokines and chemokines, which may lead to extensive ED among others ( Endothelial cells have emerged as key players in COVID-19 and LC pathologies

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doi: 10.1016/j.freeradbiomed.2018.12.011 21 SabatierMBirsenRLautureLMoucheSAngelinoPDehairsJet al